Fenben, a medication used to treat parasites and worms in animals, is becoming popular among people with cancer. This is because of a man named Joe Tippens, who claims that fenben and other supplements cured his stage four cancer.
However, scientific evidence is still lacking. In addition, anthelmintics are not approved to cure cancer by Health Canada.
Safe for Human Consumption
Fenben, a drug that has recently become very popular in the media, is a veterinary medication used to treat parasites and worms (roundworms, hookworms, whipworms, and tapeworms) in animals. It is known by brand names such as Panacur C and Safe-Guard. It belongs to a group of drugs called the benzimidazole carbamate anthelmintic family and has been in use for nearly six decades.
It has a long track record of safety in humans, and it is very effective against the various kinds of parasites that can infect dogs and other species. However, the effects of fenben on cancer have not been studied very extensively.
Nevertheless, recent reports of people using fenben to treat their cancers have received wide attention on social media. These claims are based on anecdotal accounts of a man named Joe Tippens who was diagnosed with a type of cancer and went into remission after taking fenbendazole on a veterinarian’s recommendation.
These reports have led to questions about whether fenbendazole can be repurposed as a cancer treatment. Although the evidence for this is still lacking, fenbendazole has been shown to be effective in killing tumor cells and inhibiting their growth. Moreover, fenbendazole has also been shown to act as an anti-inflammatory and has immune-boosting properties. Consequently, it is a good candidate for repurposing as a cancer treatment.
Effective in Treating Cancer
In a study published in the journal Scientific Reports, researchers found that fenben (the chemical name for the drug is N-(6-phenylsulfanyl-1H-benzimidazol-2-yl) carbamate) can block proliferation and promote cell death in cancer cells growing in the lab. Moreover, it can also reduce the growth of tumors in animal models. Other benzimidazole drugs, such as metronidazole and tinidazole, have also been shown to be effective against certain types of cancer.
The anti-tumor effect of fenben is likely due to its ability to disrupt the structure and function of mitochondria. It inhibits mitochondrial respiration and ATP production, which in turn leads to apoptosis. Furthermore, it depletes the glycolytic pathway in cancer cells by preventing GLUT transporters from activating. In addition, it interacts with tubulin to prevent its polymerization, which is required for cellular functions.
The research suggests that fenbendazole may be a promising new treatment for cancer. However, it is important to note that there isn’t enough evidence to show that fenbendazole can cure cancer in humans. There are a number of established treatments for cancer, including radiation therapy, surgery, berberine, and sodium dichloroacetate. In addition, there isn’t sufficient evidence that fenbendazole can prevent recurrence of cancer after treatment. This is especially true for patients with hepatocellular cancer, where the growth of the cancer can be caused by other factors beyond the effect of fenbendazole.
Effective in Treating Parasites
Fenben is a widely used anthelmintic drug that effectively treats parasites and worms in humans and animals. It is a member of the benzimidazole family and has been shown to kill tapeworms, hookworms, whipworms, and roundworms in both humans and animals. It also has anti-inflammatory properties and has been shown to help prevent autoimmune diseases, gastrointestinal tract inflammation, and eczema in patients with psoriasis.
Benzimidazoles, including fenbendazole, are known to block microtubule polymerization in cells. Microtubules (MT) are a critical cellular organising mechanism and are involved in cell division, motility, intercellular transport of organelles, the maintenance of a cell shape, and secretion processes in all living organisms. By binding to beta-tubulin, fenbendazole (FZ) inhibits the formation of MT in parasite cells, which disrupts a number of vital functions and eventually leads to the death of the parasite.
The FZ antitumor activity is mainly due to the disruption of MT dynamics in cancer cells, which is a result of the inhibition of glucose uptake and depletion of glycogen reserves . Its effect on glucose uptake is associated with its ability to inhibit the expression of glycolytic enzymes and GLUT transporters.
Although many studies have found that anthelmintics could be effective cancer treatments, the results are inconclusive. However, the similarities between parasitic behavior and that of cancer cells suggest that anthelmintics can play an important role in fighting cancer.
Effective in Treating Multiple Diseases
Fenben is a broad-spectrum anthelmintic in the benzimidazole carbamate family. It has been used for more than six decades to treat parasitic worms. It is safe to take with other medications and has few side effects. The drug can be purchased online and in stores. Purchasing it from a reputable seller is important to ensure that you are getting the proper dose. It is also important to minimize the number of supplements you take while taking the medication.
The antiparasitic activity of fenbendazole is mediated by binding to b-tubulin microtubule subunits and disrupting their polymerization. It has been repurposed as an anticancer agent in several studies by disrupting the MT dynamics of cancer cells, and inhibiting cell proliferation and inducing apoptosis. It has been shown to be effective in a number of different human cancer cell lines.
Although there are some scientific studies showing that fenbendazole can slow down cancer cell growth in vitro, the fact that it can do so is not sufficient evidence that it can cure cancer in humans. Furthermore, Tippens’ anecdotal experience may have been influenced by other factors, such as the other conventional cancer treatments he was receiving, which aren’t being accounted for. In order to have more definitive proof that fenben can cure cancer, randomized clinical trials must be conducted. Until then, it’s best to follow the advice of your health care professional. fenben for humans